Dichloromethane → 6-((4-chlorophenyl)(hydroxy)(1-methyl-1H-imidazol-5-yl)methyl)-1-methyl-4-(3-((trimethylsilyl)ethynyl)phenyl)-1,8-naphthyridin-2(1H)-one

반응식

[Br:1][c:2]1[cH:3][n:4][cH:5][n:6]1[CH3:7].[CH:8]([N:9]([CH2:10][CH3:11])[CH:12]([CH3:13])[CH3:14])([CH3:15])[CH3:16].[Cl:17][c:18]1[cH:19][cH:20][c:21]([C:22](=[O:23])[c:24]2[cH:25][c:26]3[c:27](-[c:36]4[cH:37][c:38]([C:42]#[C:43][Si:44]([CH3:45])([CH3:46])[CH3:47])[cH:39][cH:40][cH:41]4)[cH:28][c:29](=[O:35])[n:30]([CH3:34])[c:31]3[n:32][cH:33]2)[cH:48][cH:49]1.[Cl:50][CH2:51][Cl:52]>>[c:2]1([C:22]([c:21]2[cH:20][cH:19][c:18]([Cl:17])[cH:49][cH:48]2)([OH:23])[c:24]2[cH:25][c:26]3[c:27](-[c:36]4[cH:37][c:38]([C:42]#[C:43][Si:44]([CH3:45])([CH3:46])[CH3:47])[cH:39][cH:40][cH:41]4)[cH:28][c:29](=[O:35])[n:30]([CH3:34])[c:31]3[n:32][cH:33]2)[cH:3][n:4][cH:5][n:6]1[CH3:7]