Acetate → 3-(6-Amino-5-piperidin-1-ylmethyl-pyridin-3-yl)acrylic acid tert-butyl ester

HRID 1219610노트

반응식

[Br:1][c:2]1[cH:3][c:4]([CH2:9][N:10]2[CH2:11][CH2:12][CH2:13][CH2:14][CH2:15]2)[c:5]([NH2:8])[n:6][cH:7]1.[C:16]([CH:17]=[CH2:18])(=[O:19])[O:20][C:21]([CH3:22])([CH3:23])[CH3:24].[O-:26][C:27]([CH3:28])=[O:29].[O-:30][C:31]([CH3:32])=[O:33].[Pd+2:25]>>[c:2]1([CH:18]=[CH:17][C:16](=[O:19])[O:20][C:21]([CH3:22])([CH3:23])[CH3:24])[cH:3][c:4]([CH2:9][N:10]2[CH2:11][CH2:12][CH2:13][CH2:14][CH2:15]2)[c:5]([NH2:8])[n:6][cH:7]1