2-Methoxypyrimidine-5-boronic acid → 2-(4-fluorophenyl)-N-[3-(2-methoxypyrimidin-5-yl)pyrazolo[1,5-a]pyrimidin-2-yl]acetamide

반응식

[Br:1][c:2]1[c:3]([NH:11][C:12]([CH2:13][c:14]2[cH:15][cH:16][c:17]([F:20])[cH:18][cH:19]2)=[O:21])[n:4][n:5]2[c:6]1[n:7][cH:8][cH:9][cH:10]2.[CH3:22][O:23][c:24]1[n:25][cH:26][c:27]([B:30]([OH:31])[OH:32])[cH:28][n:29]1>>[c:2]1(-[c:27]2[cH:26][n:25][c:24]([O:23][CH3:22])[n:29][cH:28]2)[c:3]([NH:11][C:12]([CH2:13][c:14]2[cH:15][cH:16][c:17]([F:20])[cH:18][cH:19]2)=[O:21])[n:4][n:5]2[c:6]1[n:7][cH:8][cH:9][cH:10]2

참가 물질

반응물 2

HCID 27367782-Methoxypyrimidine-5-boronic acid

HCID 68749921N-(3-bromopyrazolo[1,5-a]pyrimidin-2-yl)-2-(4-fluorophenyl)acetamide

생성물 1

HCID 687528552-(4-fluorophenyl)-N-[3-(2-methoxypyrimidin-5-yl)pyrazolo[1,5-a]pyrimidin-2-yl]acetamide

출처 및 근거

ORD 기록: ord-71d64ab79e3442b1a6ec622fb676d389
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (5/10)
DOI: 10.1039/C8SC04228D

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