(3,5-Dimethoxyphenyl)methanamine → HCID 68583684, 화합물

HRID 12364

반응식

HRID 12364 반응식
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:8]=[C:9]([O:11][CH3:12])[CH:10]=1)[CH2:6][NH2:7].[CH2:13]([O:15][C:16]([C:18]1[C:19](=[O:38])[C:20]2[CH:25]=[N:24][C:23](S(C)(=O)=O)=[N:22][C:21]=2[N:30]([CH:32]2[CH2:37][CH2:36][CH2:35][CH2:34][CH2:33]2)[CH:31]=1)=[O:17])[CH3:14]>>[CH2:13]([O:15][C:16]([C:18]1[C:19](=[O:38])[C:20]2[CH:25]=[N:24][C:23]([NH:7][CH2:6][C:5]3[CH:8]=[C:9]([O:11][CH3:12])[CH:10]=[C:3]([O:2][CH3:1])[CH:4]=3)=[N:22][C:21]=2[N:30]([CH:32]2[CH2:37][CH2:36][CH2:35][CH2:34][CH2:33]2)[CH:31]=1)=[O:17])[CH3:14]

참가 물질

3

반응물 2

HCID 420973(3,5-Dimethoxyphenyl)methanamineHCID 252234828-Cyclohexyl-2-methanesulfonyl-5-oxo-5,8-dihydro-pyrido[2,3-d]pyrimidine-6-carboxylic acid ethyl ester

생성물 1

HCID 68583684HCID 68583684, 화합물

실험 절차

Using the procedure outlined in Example 28 Step F, the title compound was prepared from 3,5-dimethoxy-benzylamine and 8-cyclohexyl-2-methanesulfonyl-5-oxo-5,8-dihydro-pyrido[2,3-d]pyrimidine-6-carboxylic acid ethyl ester (33 mg, 0.08 mmol). 8-Cyclohexyl-5-oxo-2-(3,5-dimethoxy-benzylamino)-5,8-dihydro-pyrido[2,3-d]pyrimidine-6-carboxylic acid ethyl ester was obtained as a white solid (29 mg, 90%). Mass Spectrum (LCMS, ESI pos.) Calcd. For C25H30N4O5: 467.22 (M+H). Found: 467.2.

출처 및 근거

ORD 기록
ord-0cd2521c5a3847ab8129827e4d8d4efa
출처 데이터셋
uspto-grants-2010_06
특허 번호
US07728003B2

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