Acetyl chloride → Methyl 2-(2-iodophenyl)acetate

HRID 1242809

반응식

HRID 1242809 반응식
[I:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH2:8][C:9]([OH:11])=[O:10].[C:12](Cl)(=O)C>CO>[CH3:12][O:10][C:9](=[O:11])[CH2:8][C:3]1[CH:4]=[CH:5][CH:6]=[CH:7][C:2]=1[I:1]

참가 물질

4

반응물 2

HCID 6367Acetyl chlorideHCID 27800902-Iodophenylacetic acid

생성물 1

HCID 640185Methyl 2-(2-iodophenyl)acetate수율 100%

시약·촉매·용매 1

HCID 887Methanol용매

실험 절차

2-Iodophenylacetic acid (1.45 g) was added to a mixture of methanol (100 mL) and acetyl chloride (5 mL). After stirring at room temperature for 3 hours, the solvent was removed and the residue was dried under vacuum giving the desired 2-iodophenylacetic acid methyl ester. Yield=100%

후처리

  1. customthe solvent was removed
  2. customthe residue was dried under vacuum

출처 및 근거

ORD 기록
ord-9648dbe8a0734f798b9e731b9c3a0a62
출처 데이터셋
uspto-grants-2006_10
특허 번호
US07115741B2

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