HCID 332828, 화합물 → 4-(1,3-Dioxaindan-5-yl)oxane-2,6-dione
반응식
[O:1]1[C:5]2[CH:6]=[CH:7][C:8]([CH:10]([CH2:15][C:16]([OH:18])=[O:17])[CH2:11][C:12]([OH:14])=O)=[CH:9][C:4]=2[O:3][CH2:2]1>C(OC(=O)C)(=O)C>[O:1]1[C:5]2[CH:6]=[CH:7][C:8]([CH:10]3[CH2:11][C:12](=[O:14])[O:18][C:16](=[O:17])[CH2:15]3)=[CH:9][C:4]=2[O:3][CH2:2]1참가 물질
3
실험 절차
3-(1,3-benzodioxol-5-yl)pentanedioic acid (2 g, 7.9 mmoles) was suspended in acetic anhydride (50 ml) and refluxed for two hours. The reaction mixture was allowed to cool to room temperature and the solvent was removed under reduced pressure. The residue was triturated with ether to give the product (1.3 g, 70%). 1H NMR (DMSO-d6) δ 6.91 (m, 1H), 6.89 (m, 1H), 6.72 (m, 1H), 6.01 (s, 2H), 3.53–3.41 (m, 1H), 3.07–2.89 (m, 4H).
후처리
- temperaturerefluxed for two hours
- customthe solvent was removed under reduced pressure
- customThe residue was triturated with ether
출처 및 근거
- ORD 기록
- ord-b78362e570a04da3afa2180bb2364655
- 출처 데이터셋
- uspto-grants-2006_10
- 특허 번호
- US07119098B2
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