Methyl Isocyanate → HCID 20279741, 화합물

HRID 1247869노트

반응식

HRID 1247869 반응식
Cl.[CH2:2]([NH:14][NH2:15])[CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH3:13].[OH-].[K+].[CH3:18][N:19]=[C:20]=[O:21]>C(OCC)C>[CH3:18][NH:19][C:20]([N:14]([CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH3:13])[NH2:15])=[O:21]

참가 물질

5

반응물 3

HCID 12228Methyl IsocyanateHCID 14797Potassium HydroxideHCID 20279742HCID 20279742, 화합물

생성물 1

HCID 20279741HCID 20279741, 화합물수율 94.7%

시약·촉매·용매 1

HCID 3283Diethyl Ether용매2회

실험 절차

A stirred, degassed suspension of dodecylhydrazine hydrochloride (4.62 g, 0.017 mole) in diethyl ether (15 mL) was cooled under nitrogen and 4N aqueous potassium hydroxide (8.7 mL, 0.035 mole) was added. Stirring was continued as methyl isocyanate (0.97 g, 0.017 mole) in 5 mL diethyl ether was added dropwise. The mixture was filtered to yield 4.12 g (94.7%) N-methyl-1-dodecyl-hydrazinecarboxamide (m.p. 73°-75° C.). NMR analysis confirmed the structure.

후처리

  1. customA stirred, degassed
  2. temperaturewas cooled under nitrogen
  3. additionwas added dropwise
  4. filtrationThe mixture was filtered

출처 및 근거

ORD 기록
ord-65043bcda5634aca90dd0bcf9f2fa99c
출처 데이터셋
uspto-grants-1985_06
특허 번호
US04521325

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