Dimethyl Sulfoxide → tert-butyl 3-{[5-fluoro-2-(methoxymethyl)pyrimidin-4-yl]amino}-6,6-dimethyl-4,6-dihydropyrrolo[3,4-c]pyrazole-5(1H)-carboxylate

HRID 124937노트

반응식

[CH3:35][S:36]([CH3:37])=[O:38].[Cl:19][c:20]1[n:21][c:22]([CH2:27][O:28][CH3:29])[n:23][cH:24][c:25]1[F:26].[NH2:1][c:2]1[c:3]2[c:4]([nH:5][n:6]1)[C:7]([CH3:17])([CH3:18])[N:8]([C:10](=[O:11])[O:12][C:13]([CH3:14])([CH3:15])[CH3:16])[CH2:9]2.[Na+:34].[O-:30][C:31]([OH:32])=[O:33]>>[NH:1]([c:2]1[c:3]2[c:4]([nH:5][n:6]1)[C:7]([CH3:17])([CH3:18])[N:8]([C:10](=[O:11])[O:12][C:13]([CH3:14])([CH3:15])[CH3:16])[CH2:9]2)[c:20]1[n:21][c:22]([CH2:27][O:28][CH3:29])[n:23][cH:24][c:25]1[F:26]