Dimethyl Sulfoxide → p-Methylcinnamaldehyde

HRID 12534

반응식

HRID 12534 반응식
C(Cl)(=O)C(Cl)=O.CS(C)=O.[CH3:11][C:12]1[CH:17]=[CH:16][C:15](/[CH:18]=[CH:19]/[CH2:20][OH:21])=[CH:14][CH:13]=1.C(N(CC)CC)C>C(Cl)Cl>[CH3:11][C:12]1[CH:17]=[CH:16][C:15](/[CH:18]=[CH:19]/[CH:20]=[O:21])=[CH:14][CH:13]=1

참가 물질

6

반응물 4

HCID 679Dimethyl SulfoxideHCID 8471TriethylamineHCID 65578Oxalyl chlorideHCID 53874824-Methylcinnamyl alcohol2회

생성물 1

HCID 5371802p-Methylcinnamaldehyde

시약·촉매·용매 1

HCID 6344Dichloromethane용매

실험 절차

Following General Procedure H, oxalyl chloride (7.1 ml, 14.2 mmol, 2 M in CH2Cl2), DMSO (1.3 ml, 18.9 mmol), (E)-3-(4-methylphenyl)prop-2-en-1-ol (Compound 41, 1.4 g, 9.5 mmol) and triethylamine (4.4 ml, 31.4 mmol) in CH2Cl2 (5 ml) were reacted to obtain the title compound as an oil.

후처리

  1. customwere reacted

출처 및 근거

ORD 기록
ord-ff46d30221ab41f09c751f2de95c3f11
출처 데이터셋
uspto-grants-2010_06
특허 번호
US07728014B2

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