Hydrochloric Acid → HCID 72280550, 화합물

HRID 1258444노트

반응식

HRID 1258444 반응식
Cl.[N:2]1([CH2:8][CH:9]=[CH:10][C:11]([OH:13])=O)[CH2:7][CH2:6][CH2:5][CH2:4][CH2:3]1.C(Cl)(=O)C([Cl:17])=O>ClCCl.CN(C)C=O>[N:2]1([CH2:8][CH:9]=[CH:10][C:11]([Cl:17])=[O:13])[CH2:7][CH2:6][CH2:5][CH2:4][CH2:3]1

참가 물질

6

반응물 3

HCID 313Hydrochloric AcidHCID 65578Oxalyl chlorideHCID 541093814-(1-Piperidinyl)-2-butenoic acid

생성물 1

HCID 72280550HCID 72280550, 화합물

시약·촉매·용매 2

HCID 6228Dimethylformamide촉매HCID 6344Dichloromethane용매

실험 절차

The HCl salt of 4-Piperidin-1-yl-but-2-enoic acid (250 mg, 1.48 mmol) was dissolved in dichloromethane (15 mL). Dimethylformamide (3 drops) was added. Oxalyl chloride (155 μL, 1.77 mmol) was added slowly and the reaction was stirred at room temperature for 1 hour. The mixture was concentrated under reduced pressure and the residue was used as is.

후처리

  1. concentrationThe mixture was concentrated under reduced pressure

출처 및 근거

ORD 기록
ord-1bfe9cf3067b4ac291a15040699bd326
출처 데이터셋
uspto-grants-2013_06
특허 번호
US08466165B2

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