Methanethiol → 2-Methylthio-2,4-dimethylpentan-3-one
반응식
CO.[Na].[CH3:4][SH:5].Br[C:7]([CH3:14])([C:9](=[O:13])[CH:10]([CH3:12])[CH3:11])[CH3:8]>O>[CH3:4][S:5][C:7]([CH3:14])([C:9](=[O:13])[CH:10]([CH3:12])[CH3:11])[CH3:8]참가 물질
6
실험 절차
A solution of 200 ml. of methanol containing 9.2 g. (0.40 mole) sodium metal was cooled in an ice-bath and saturated with gaseous methyl mercaptan. To this was added 77.2 g. (0.40 mole) of 2-bromo-2,4-dimethylpentan-3-one at room temperature and the resulting mixture stirred for two hours. The reaction mixture was diluted with water, extracted with ethyl ether, the extracts washed with water, brine and dried over anhydrous sodium sulfate. The ether was evaporated and the residue distilled in vacuo to afford 50.4 g. of product, B.P. 76° (20 mm.).
후처리
- additionTo this was added 77.2 g
- extractionextracted with ethyl ether
- washthe extracts washed with water, brine
- dry with materialdried over anhydrous sodium sulfate
- customThe ether was evaporated
- distillationthe residue distilled in vacuo
- customto afford 50.4 g
출처 및 근거
- ORD 기록
- ord-7f976be0716b410096afe8648eebb854
- 출처 데이터셋
- uspto-grants-1984_06
- 특허 번호
- US04454328
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