Phosphoric Acid → 4-methylbenzothiazole-5-carboxylic Acid

HRID 1263404노트

반응식

HRID 1263404 반응식
[CH3:1][C:2]1[C:7]2[N:8]=[CH:9][S:10][C:6]=2[CH:5]=[CH:4][C:3]=1[C:11]([O:13]C)=[O:12].P(=O)(O)(O)O>[OH-].[K+]>[CH3:1][C:2]1[C:7]2[N:8]=[CH:9][S:10][C:6]=2[CH:5]=[CH:4][C:3]=1[C:11]([OH:13])=[O:12]

참가 물질

4

반응물 2

HCID 1004Phosphoric AcidHCID 18616057Methyl 4-Methylbenzothiazole-5-carboxylate

생성물 1

HCID 114809704-methylbenzothiazole-5-carboxylic Acid

시약·촉매·용매 1

HCID 14797Potassium Hydroxide용매

실험 절차

16.6 g of methyl 4-methylbenzothiazole-5-carboxylate (0.08 mol) were dissolved in 280 ml of 5% strength aqueous potassium hydroxide solution and heated at reflux for 2.5 h. After cooling, the mixture was acidified using phosphoric acid. The product was filtered off and subsequently dried.

후처리

  1. temperatureheated
  2. temperatureat reflux for 2.5 h
  3. temperatureAfter cooling
  4. filtrationThe product was filtered off
  5. customsubsequently dried

출처 및 근거

ORD 기록
ord-9661301a5c1d4a79a1f6f2a60ed9e312
출처 데이터셋
uspto-grants-2003_04
특허 번호
US06541423B1

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