Dimethylamine → 5-(Dimethylamino)pentanenitrile

HRID 1264298노트

반응식

HRID 1264298 반응식
[CH3:1][NH:2][CH3:3].Br[CH2:5][CH2:6][CH2:7][CH2:8][C:9]#[N:10]>[OH-].[Na+]>[CH3:1][N:2]([CH3:3])[CH2:5][CH2:6][CH2:7][CH2:8][C:9]#[N:10]

참가 물질

4

반응물 2

HCID 674DimethylamineHCID 794355-Bromopentanenitrile

생성물 1

HCID 53056495-(Dimethylamino)pentanenitrile

시약·촉매·용매 1

HCID 14798Sodium Hydroxide용매

실험 절차

A mixture of dimethylamine (4 mL, 40% in water) and 5-bromo-pentanenitrile (2.3 mL, 20 mmol) is stirred for 24 h. The resulting reaction mixture is diluted with sodium hydroxide solution (10 mL, 5M) and extracted with ether. The ether extract is dried over K2CO3 and concentrated under reduced pressure to give an oil (1.5 g) which is used without further purification.

후처리

  1. customThe resulting reaction mixture
  2. extractionextracted with ether
  3. extractionThe ether extract
  4. dry with materialis dried over K2CO3
  5. concentrationconcentrated under reduced pressure

출처 및 근거

ORD 기록
ord-44a70acd3b3c45d787ed0e4e7e0076b1
출처 데이터셋
uspto-grants-2003_04
특허 번호
US06541505B1

반응 노트

불러오는 중…