HCID 69688164, 화합물 → (2-Amino-5-azetidin-1-yl-4-trifluoromethyl-phenyl)-carbamic acid tert.-butyl ester
반응식
[C:1]([O:5][C:6](=[O:25])[NH:7][C:8]1[CH:13]=[C:12]([N:14]2[CH2:17][CH2:16][CH2:15]2)[C:11]([C:18]([F:21])([F:20])[F:19])=[CH:10][C:9]=1[N+:22]([O-])=O)([CH3:4])([CH3:3])[CH3:2]>[Pt]>[C:1]([O:5][C:6](=[O:25])[NH:7][C:8]1[CH:13]=[C:12]([N:14]2[CH2:17][CH2:16][CH2:15]2)[C:11]([C:18]([F:20])([F:21])[F:19])=[CH:10][C:9]=1[NH2:22])([CH3:4])([CH3:2])[CH3:3]참가 물질
3
실험 절차
The title compound was prepared from (5-azetidin-1-yl-2-nitro-4-trifluoromethyl-phenyl)-carbamic acid tert.-butyl ester (Example C15) by hydrogenation with 5% Pt/C according to the general procedure J (method a).
출처 및 근거
- ORD 기록
- ord-768a41e64e304823a51595db700ce21f
- 출처 데이터셋
- uspto-grants-2003_04
- 특허 번호
- US06544985B2
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