Sodium borohydride → [1-(3-Amino-4-nitro-phenyl)-1H-pyrrol-3-yl]-methanol

HRID 1266739노트

반응식

HRID 1266739 반응식
[NH2:1][C:2]1[CH:3]=[C:4]([N:11]2[CH:15]=[CH:14][C:13]([CH:16]=[O:17])=[CH:12]2)[CH:5]=[CH:6][C:7]=1[N+:8]([O-:10])=[O:9].[BH4-].[Na+]>CCO>[NH2:1][C:2]1[CH:3]=[C:4]([N:11]2[CH:15]=[CH:14][C:13]([CH2:16][OH:17])=[CH:12]2)[CH:5]=[CH:6][C:7]=1[N+:8]([O-:10])=[O:9]

참가 물질

4

반응물 2

HCID 4311764Sodium borohydrideHCID 18548903HCID 18548903, 화합물

생성물 1

HCID 18548757[1-(3-Amino-4-nitro-phenyl)-1H-pyrrol-3-yl]-methanol

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

The title compound was prepared from 1-(3-amino-4-nitro-phenyl)-1H-pyrrole-3-carbaldehyde (Example F4) by reduction with 2 eq. NaBH4 in EtOH at 23° C. for 30 min. Obtained as a brown solid (20 mg).

출처 및 근거

ORD 기록
ord-6d6b01645ae8489bae3b85b4e52549c4
출처 데이터셋
uspto-grants-2003_04
특허 번호
US06548495B2

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