Trifluoroacetic anhydride → HCID 22224751, 화합물

HRID 1266774노트

반응식

HRID 1266774 반응식
[C:1]([O:5][C:6](=[O:18])[CH2:7][C:8]([C:10]1[CH:15]=[CH:14][N:13]=[C:12]([C:16]#[N:17])[CH:11]=1)=[O:9])(C)([CH3:3])[CH3:2].C(OC(C(F)(F)F)=O)(C(F)(F)F)=O>C(O)(C(F)(F)F)=O.CC(C)=O>[CH3:2][C:1]1([CH3:3])[O:9][C:8]([C:10]2[CH:15]=[CH:14][N:13]=[C:12]([C:16]#[N:17])[CH:11]=2)=[CH:7][C:6](=[O:18])[O:5]1

참가 물질

4

반응물 2

HCID 9845Trifluoroacetic anhydrideHCID 695928163-(2-Cyano-pyridin-4-yl)-3-oxo-propionic acid tert-butyl ester

생성물 1

HCID 22224751HCID 22224751, 화합물

시약·촉매·용매 1

HCID 86586799TFA acetone용매

실험 절차

The title compound was prepared from 3-(2-cyano-pyridin-4-yl)-3-oxo-propionic acid tert.-butyl ester (Example M10) by stirring in TFA/acetone with TFAA according to general procedure L (method b). Obtained as a brown solid (3.30 g).

출처 및 근거

ORD 기록
ord-64c531f3366740928d9be48e73736cf5
출처 데이터셋
uspto-grants-2003_04
특허 번호
US06548495B2

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