Acetic Anhydride → HCID 20529234, 화합물

HRID 126896노트

반응식

HRID 126896 반응식
[CH3:1][NH:2][CH:3]1[CH2:15][CH2:14][C:13]2[C:12]3[C:7](=[CH:8][CH:9]=[CH:10][CH:11]=3)[NH:6][C:5]=2[CH2:4]1.C(O[C:20](=[O:22])[CH3:21])(=O)C>>[CH2:4]1[C:5]2[NH:6][C:7]3[C:12](=[CH:11][CH:10]=[CH:9][CH:8]=3)[C:13]=2[CH2:14][CH2:15][CH:3]1[N:2]([CH3:1])[C:20](=[O:22])[CH3:21]

참가 물질

3

반응물 2

HCID 7918Acetic AnhydrideHCID 20529239HCID 20529239, 화합물

생성물 1

HCID 20529234HCID 20529234, 화합물

실험 절차

A mixture of 10.0 g (0.05 mol) of 2,3,4,9-tetrahydro-N-methyl-1H-carbazol-2-amine and 70 ml of acetic anhydride was heated at reflux until complete solution occurred (2-3 min). After standing overnight at room temperature and further cooling at 0°, the precipitated solid was filtered, washed first with small portions of cold acetic anhydride and then thoroughly with anhydrous ether. The crude product was recrystallized from ethanol to give the title compound, mp 215°-216°.

후처리

  1. temperaturewas heated
  2. temperatureat reflux until complete solution
  3. custom(2-3 min)
  4. temperaturefurther cooling at 0°
  5. filtrationthe precipitated solid was filtered
  6. washwashed first with small portions of cold acetic anhydride
  7. customThe crude product was recrystallized from ethanol

출처 및 근거

ORD 기록
ord-04450d90296e48e4801f9a0315f6a30c
출처 데이터셋
uspto-grants-1981_03
특허 번호
US04254134

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