Hexamethylphosphoramide → 1-Ethoxyethyl 4-(hexadecylamino)benzoate

HRID 126954

반응식

HRID 126954 반응식
Cl[CH:2]([O:4][CH2:5][CH3:6])[CH3:3].[CH2:7]([NH:23][C:24]1[CH:32]=[CH:31][C:27]([C:28]([O-:30])=[O:29])=[CH:26][CH:25]=1)[CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH3:22].[Na+].CN(C)P(N(C)C)(N(C)C)=O>O>[CH2:7]([NH:23][C:24]1[CH:25]=[CH:26][C:27]([C:28]([O:30][CH:2]([O:4][CH2:5][CH3:6])[CH3:3])=[O:29])=[CH:31][CH:32]=1)[CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH3:22]

참가 물질

5

반응물 3

HCID 12679HexamethylphosphoramideHCID 23478Ethane, 1-chloro-1-ethoxy-HCID 23703815Cetaben Sodium

생성물 1

HCID 234577741-Ethoxyethyl 4-(hexadecylamino)benzoate

시약·촉매·용매 1

HCID 962Water용매

실험 절차

A mixture of 22.0 g. of ethyl 1-chloroethyl ether, 77.0 g. of sodium 4-(hexadecylamino)benzoate and 250 ml. of hexamethylphosphoramide is stirred at 20° C. for 24 hours. After slow addition of water to the crystallization point and standing for 3 hours, the acetal ester is collected on a filter.

후처리

  1. additionA mixture of 22.0 g
  2. customthe acetal ester is collected on a filter

출처 및 근거

ORD 기록
ord-d2f27402a5184963a1bbf7e778f3be30
출처 데이터셋
uspto-grants-1981_03
특허 번호
US04254138

연결된 노트

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