Hydrochloric Acid → HCID 18448751, 화합물

HRID 1269576노트

반응식

HRID 1269576 반응식
[Br:1][C:2]1[CH:3]=[C:4]([O:19]C)[CH:5]=[C:6]([Br:18])[C:7]=1[O:8][C:9]1[CH:14]=[CH:13][C:12]([N+:15]([O-:17])=[O:16])=[CH:11][CH:10]=1.Cl>ClCCl>[Br:1][C:2]1[CH:3]=[C:4]([OH:19])[CH:5]=[C:6]([Br:18])[C:7]=1[O:8][C:9]1[CH:10]=[CH:11][C:12]([N+:15]([O-:17])=[O:16])=[CH:13][CH:14]=1

참가 물질

4

반응물 2

HCID 313Hydrochloric AcidHCID 18448749HCID 18448749, 화합물

생성물 1

HCID 18448751HCID 18448751, 화합물

시약·촉매·용매 1

HCID 6344Dichloromethane용매3회

실험 절차

Boronitribromide (12 mL, 1 N in dichloromethane) was added to a cooled mixture of 3,5-dibromo-4-(4-nitrophenoxy)anisole (2.0 g) in dichloromethane (50 mL) and left for 16 hours at room temperature. Hydrochloric acid (2 N) was added and the reaction mixture was heated at reflux for 15 minutes. The reaction mixture was diluted with dichloromethane, washed with water and concentrated. Quantitative yield of 3,5-dibromo-4-(4-nitrophenoxy) phenol was obtained.

후처리

  1. temperaturethe reaction mixture was heated
  2. temperatureat reflux for 15 minutes
  3. washwashed with water
  4. concentrationconcentrated

출처 및 근거

ORD 기록
ord-ebc2ce698b5d42b4b2802c03409f5693
출처 데이터셋
uspto-grants-2007_04
특허 번호
US07199265B2

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