1-Bromo-3-chloropropane → 1-(3-Chloropropyl)-4-methylpiperidin-4-ol

반응식

[CH3:1][C:2]1([OH:8])[CH2:7][CH2:6][NH:5][CH2:4][CH2:3]1.Br[CH2:10][CH2:11][CH2:12][Cl:13]>>[Cl:13][CH2:12][CH2:11][CH2:10][N:5]1[CH2:6][CH2:7][C:2]([CH3:1])([OH:8])[CH2:3][CH2:4]1

참가 물질

반응물 2

HCID 80061-Bromo-3-chloropropane

HCID 156491744-Methylpiperidin-4-ol

생성물 1

HCID 184498301-(3-Chloropropyl)-4-methylpiperidin-4-ol

실험 절차

4-methylpiperidin-4-ol (made via literature methods) and 1-bromo-3-chloropropane are reacted using the procedure for Example OO to afford 1-(3-chloropropyl)-4-methylpiperidin-4-ol.

출처 및 근거

ORD 기록: ord-756bab24e01845099a438f8c60eb25cb
출처 데이터셋: uspto-grants-2007_04
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07202257B2

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