Propylene Oxide → 1-(2-Benzyl-4-chlorophenoxy)propan-2-ol

HRID 127122

반응식

HRID 127122 반응식
[CH2:1]([C:8]1[CH:13]=[C:12]([Cl:14])[CH:11]=[CH:10][C:9]=1[OH:15])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH2:16]1[O:19][CH:17]1[CH3:18]>[OH-].[Na+]>[CH2:1]([C:8]1[CH:13]=[C:12]([Cl:14])[CH:11]=[CH:10][C:9]=1[O:15][CH2:16][CH:17]([OH:19])[CH3:18])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

참가 물질

4

반응물 2

HCID 6378Propylene OxideHCID 8425Chlorophene

생성물 1

HCID 202860201-(2-Benzyl-4-chlorophenoxy)propan-2-ol

시약·촉매·용매 1

HCID 14798Sodium Hydroxide촉매

실험 절차

2-Benzyl-4-chlorophenol (43.7 parts) is propoxylated with propylene oxide (12.6 parts) using sodium hydroxide (0.2 part) as catalyst at 145° C. in a manner similar to that used in Example 10 to give 1-(2-benzyl-4-chlorophenoxy)propan-2-ol (16.3 parts)

후처리

  1. customat 145° C.

출처 및 근거

ORD 기록
ord-e058165be7c8495780fba51b6de57c84
출처 데이터셋
uspto-grants-1981_03
특허 번호
US04255152

연결된 노트

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