참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Isopropanol | HCID 3776 | — |
| 반응물 | 4-Chloro-3-hydroxybenzoic acid | HCID 141872 | — |
| 생성물 | 4-Chloro-3-hydroxy-benzoic acid isopropyl ester | HCID 69418989 | 75% |
반응 단계
4-Chloro-3-hydroxy-benzoic acid (100 mg, 0.58 mmol) and 1 mL of isopropanol were mixed and then heated to 85° C. for overnight. The mixture was then concentrated in vacuum and the resulting residue was purified by flash chromatography (8–20% EtOAc/Hex) to give the desired ester (94 mg, 75%). MS (DCI) m/z 215 (M+H)+, 232 (M+NH4)+.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US07205409B2 |
|---|
| 출처 데이터셋 | uspto-grants-2007_04 |
|---|
| ORD ID | ord-d160994da4dc4be5bb9d588354b12d3d |
|---|
| 출처 메모 | uspto-grants-2007_04 |
|---|
