Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Cysteamine Hydrochloride → 2-(((5-Methyl-1H-imidazol-4-yl)methyl)thio)ethylamine dihydrochloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Cysteamine Hydrochloride | HCID 9082 | — |
| 반응물 | 4-Methylimidazol-5-ylmethanolhydrochloride | HCID 3084707 | — |
| 용매 | Acetic Acid | HCID 176 | — |
| 생성물 | 2-(((5-Methyl-1H-imidazol-4-yl)methyl)thio)ethylamine dihydrochloride | HCID 3015999 | 184.6% |
반응 단계
A solution of 4-hydroxymethyl-5-methylimidazole hydrochloride (30 g) and cysteamine hydrochloride (23 g) in acetic acid (200 ml) was heated under reflux for 10 hours. Following cooling to 15°-20° C., the solid which crystallised was collected and washed with isopropyl alcohol to give 2[(5-methylimidazol-4-yl)methyl]thioethylamine dihydrochloride (45.5 g), m.p. 189°-192° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04255425 |
| 출처 데이터셋 | uspto-grants-1981_03 |
| ORD ID | ord-3182308200444c808de3514923d8ef8d |
| 출처 메모 | uspto-grants-1981_03 |