돌아가기
Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 127206생성일: 2026년 10월 26일

Ethanol → 2-[2-(5-Methyl-4-imidazolylmethylthio)ethylamino]-5-(4-methoxy-2-pyridylmethyl)-4-pyrimidone

https://huagongshe.com/reaction/127206

반응식

참여 물질

역할이름HCID투입량
반응물EthanolHCID 702—
반응물4-(((2-Aminoethyl)thio)methyl)-5-methylimidazoleHCID 665568—
반응물2-Nitroamino-5-(4-methoxy-2-pyridylmethyl)-4-pyrimidoneHCID 12783834—
용매IsopropanolHCID 3776—
생성물2-[2-(5-Methyl-4-imidazolylmethylthio)ethylamino]-5-(4-methoxy-2-pyridylmethyl)-4-pyrimidoneHCID 12788678—

반응 단계

Reaction of 2-nitroamino-5-(4-methoxy-2-pyridylmethyl)-4-pyrimidone with 1.06 molar equivalents of 2-(5-methyl-4-imidazolylmethylthio)ethylamine in refluxing ethanol for 24 hours gave 2-[2-(5-methyl-4-imidazolylmethylthio)ethylamino]-5-(4-methoxy-2-pyridylmethyl)-4-pyrimidone, m.p. 128-130° (from 2-propanol).

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US04255428
출처 데이터셋uspto-grants-1981_03
ORD IDord-06d75e9eee97420e980a2f62bef5b330
출처 메모uspto-grants-1981_03