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HRID127206

反应详情

EQUATION

反应方程式

HRID 127206 的结构方程式

REACTANTS

反应物

3
结构：CCO
HCID702

Ethanol

C2H6O

结构：Cc1[nH]cnc1CSCCN
HCID665568

4-(((2-Aminoethyl)thio)methyl)-5-methylimidazole

C7H13N3S

结构：COc1ccnc(Cc2cnc(N[N+](=O)[O-])[nH]c2=O)c1
HCID12783834

未命名化合物

PRODUCTS

生成物

1
结构：COc1ccnc(Cc2cnc(NCCSCc3nc[nH]c3C)[nH]c2=O)c1
HCID12788678

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CC(C)O
溶剂HCID3776

Isopropanol

C3H8O

PROCEDURE

实验过程

Reaction of 2-nitroamino-5-(4-methoxy-2-pyridylmethyl)-4-pyrimidone with 1.06 molar equivalents of 2-(5-methyl-4-imidazolylmethylthio)ethylamine in refluxing ethanol for 24 hours gave 2-[2-(5-methyl-4-imidazolylmethylthio)ethylamino]-5-(4-methoxy-2-pyridylmethyl)-4-pyrimidone, m.p. 128-130° (from 2-propanol).