Acetic Anhydride → 4-Phenyloxane-2,6-dione

HRID 1272270노트

반응식

C(OC(=O)C)(=O)C.[C:8]1([CH:14]([CH2:19][C:20]([OH:22])=[O:21])[CH2:15][C:16]([OH:18])=O)[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1>>[C:8]1([CH:14]2[CH2:15][C:16](=[O:18])[O:22][C:20](=[O:21])[CH2:19]2)[CH:9]=[CH:10][CH:11]=[CH:12][CH:13]=1

참가 물질

반응물 2

HCID 7918Acetic Anhydride

HCID 778233-Phenylglutaric acid

생성물 1

HCID 2978824-Phenyloxane-2,6-dione수율 90%

실험 절차

To acetic anhydride (5 ml) was added 3-phenylglutaric acid (2.20 g, 10.6 mmol). The mixture was refluxed for 3 hours. The resulting mixture was concentrated under reduced pressure. The residue was crystallized from diisopropyl ether to obtain 1.8 g (yield 90%) of the title compound.

후처리

temperatureThe mixture was refluxed for 3 hours
concentrationThe resulting mixture was concentrated under reduced pressure
customThe residue was crystallized from diisopropyl ether

출처 및 근거

ORD 기록: ord-820d357ea1494a86a48756c219c7c12a
출처 데이터셋: uspto-grants-2007_04
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07208495B2

반응 노트

불러오는 중…