5-((Dimethylamino)methyl)-2-furanmethanol → Ranisen

HRID 127326

반응식

HRID 127326 반응식
[SH:1][CH2:2][CH2:3][NH:4][C:5]([NH:10][CH3:11])=[CH:6][N+:7]([O-:9])=[O:8].[CH3:12][N:13]([CH2:15][C:16]1[O:20][C:19]([CH2:21]O)=[CH:18][CH:17]=1)[CH3:14]>Cl.O.C(=O)([O-])[O-].[K+].[K+]>[CH3:12][N:13]([CH2:15][C:16]1[O:20][C:19]([CH2:21][S:1][CH2:2][CH2:3][NH:4][C:5]([NH:10][CH3:11])=[CH:6][N+:7]([O-:9])=[O:8])=[CH:18][CH:17]=1)[CH3:14]

참가 물질

6

반응물 2

HCID 849065-((Dimethylamino)methyl)-2-furanmethanolHCID 181798N-(2-Mercaptoethyl)-N'-methyl-2-nitro-1,1-ethenediamine

생성물 1

HCID 5039Ranisen

시약·촉매·용매 3

HCID 313Hydrochloric Acid용매HCID 962Water용매HCID 11430Potassium Carbonate용매

실험 절차

N-(2-Mercaptoethyl)-N'-methyl-2-nitro-1,1-ethenediamine (354 mg) in concentrated hydrochloric acid (2 ml) was added dropwise to 5-(dimethylamino)methyl-2-furanmethanol (428 mg) at 0°. After standing at 0° for 7 days the reaction was diluted with water (3 ml), excess potassium carbonate was added and the solid extracted with ethyl acetate (50 ml).

후처리

  1. additionwas added
  2. extractionthe solid extracted with ethyl acetate (50 ml)

출처 및 근거

ORD 기록
ord-7b52a0cb7e804b8b96ef01935898f3ae
출처 데이터셋
uspto-grants-1981_03
특허 번호
US04255440

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