Phosphorus tribromide → 1-(Bromomethyl)-2,3-dimethylbenzene

HRID 1275904노트

반응식

HRID 1275904 반응식
O[CH2:2][C:3]1[CH:8]=[CH:7][CH:6]=[C:5]([CH3:9])[C:4]=1[CH3:10].P(Br)(Br)[Br:12]>C1C=CC=CC=1.C1(C)C=CC=CC=1>[Br:12][CH2:2][C:3]1[CH:8]=[CH:7][CH:6]=[C:5]([CH3:9])[C:4]=1[CH3:10]

참가 물질

5

반응물 2

HCID 24614Phosphorus tribromideHCID 96208(2,3-Dimethylphenyl)methanol

생성물 1

HCID 1136271-(Bromomethyl)-2,3-dimethylbenzene

시약·촉매·용매 2

HCID 241Benzene용매HCID 1140Toluene용매

실험 절차

A mixture of 1-hydroxymethyl-2,3-dimethylbenzene (ref) (5 g) and phosphorous tribromide (1.16 ml) in benzene (50 ml) was heated at reflux for 3 hours. The mixture was diluted with toluene, washed with water, dried (MgSO4) and evaporated. Yield 7 g.

후처리

  1. temperaturewas heated
  2. temperatureat reflux for 3 hours
  3. washwashed with water
  4. dry with materialdried (MgSO4)
  5. customevaporated

출처 및 근거

ORD 기록
ord-f25708848ecf4d70a9b64b1ebba36797
출처 데이터셋
uspto-grants-2000_12
특허 번호
US06162808

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