Triethylamine → 3-Isoxazolamine, 5-(1,1-dimethylethyl)-
반응식
[C:1]([CH2:7][C:8]#[N:9])(=[O:6])[C:2]([CH3:5])([CH3:4])[CH3:3].C([N:12](CC)CC)C.S(O)(O)(=O)=O.NO>O>[NH2:9][C:8]1[CH:7]=[C:1]([C:2]([CH3:5])([CH3:4])[CH3:3])[O:6][N:12]=1참가 물질
5
실험 절차
A suspension of pivaloylacetonitrile (12.52 g) and triethylamine (11.27 g) in water (200 ml) is stirred and mixed with hydroxylamine sulfate (9.03 g). pH 8.22. The reaction mixture is treated as in Example 2 to give 3-amino-5-t-butylisoxazole (11.45 g; yield, 81.7%).
후처리
- additionThe reaction mixture is treated as in Example 2
출처 및 근거
- ORD 기록
- ord-d73c023895844ceaa0b5ec960b928bde
- 출처 데이터셋
- uspto-grants-1981_03
- 특허 번호
- US04256899
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