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Water → HCID 54504210, 화합물

HRID 1278040
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HRID 1278040 반응식
[Na].COS([O-])(=O)=O.CN(C)[C:10]1[CH2:14][CH2:13][CH2:12][N+:11]=1[CH2:15][C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1.[CH2:23]([O:25][C:26](=[O:38])[CH2:27][C:28]1[CH:37]=[CH:36][C:33]([O:34][CH3:35])=[C:30]([O:31][CH3:32])[CH:29]=1)[CH3:24].O>C(O)C.C(OCC)C>[CH2:15]([N:11]1[CH2:12][CH2:13][CH2:14][C:10]1=[C:27]([C:26]([O:25][CH2:23][CH3:24])=[O:38])[C:28]1[CH:37]=[CH:36][C:33]([O:34][CH3:35])=[C:30]([O:31][CH3:32])[CH:29]=1)[C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1
참가 물질실험 절차후처리출처 및 근거반응 노트

참가 물질

7

반응물 4

HCID 962WaterHCID 87441Ethyl 3,4-dimethoxyphenylacetateHCID 5360545SodiumHCID 178483029HCID 178483029, 화합물

생성물 1

HCID 54504210HCID 54504210, 화합물

시약·촉매·용매 2

HCID 702Ethanol용매
HCID 3283
Diethyl Ether
용매

실험 절차

Add (dropwise at 90°, with stirring, in a stream of nitrogen) a solution of 2.6 g of sodium in 50 ml of ethanol to 34.5 g of 2-dimethylamino-1-benzyl-1-pyrroliniummethylsulfate and 19.7 g of homoveratric acid ethyl ester. Keep the resulting reaction mixture at this temperature for a further 30 minutes and then distribute it between water and diethyl ether. Dry the ether solution over sodium sulfate and then concentrate it to obtain a yield [32.2 g (96% of theory)] of title compound.

후처리

  1. additionAdd (dropwise at 90°
  2. customthe resulting reaction mixture at this temperature for a further 30 minutes
  3. dry with materialDry the ether solution over sodium sulfate
  4. concentrationconcentrate it
  5. customto obtain

출처 및 근거

ORD 기록
ord-250d87d96f8449d2b2e97c81c080b393
출처 데이터셋
uspto-grants-1981_07
DOI
10.6084/m9.figshare.5104873.v1
특허 번호
US04279918

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