Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-Chlorobenzyl cyanide → 2-(alpha-Cyano-4-chlorobenzylidene)-1-methylpyrrolidine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-Chlorobenzyl cyanide | HCID 241582 | — |
| 반응물 | 2,2-Diethoxy-1-methylpyrrolidine | HCID 297308 | — |
| 용매 | Benzene | HCID 241 | — |
| 생성물 | 2-(alpha-Cyano-4-chlorobenzylidene)-1-methylpyrrolidine | HCID 53867175 | — |
반응 단계
Boil 22.7 g of 2,2-diethoxy-1-methylpyrrolidine, 19.8 g of 4-chlorobenzylcyanide and 90 ml of benzene for 1 hour under reflux and with stirring. Distil off the volatile constituents under a vacuum. After trituration with a little diethyl ether, filter off the residue to obtain 20.8 g (68% of theory) and the title compound (m.p. 71° to 72° from isopropanol).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04279918 |
| 출처 데이터셋 | uspto-grants-1981_07 |
| ORD ID | ord-38d157ccb44247ad82d5a58cc7c67f0b |
| 출처 메모 | uspto-grants-1981_07 |