Glycol monoethyl ether → HCID 21163083, 화합물

HRID 1278236노트

반응식

HRID 1278236 반응식
[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([C:7]2[N:12]3[N:13]=[CH:14][C:15]([C:16]([O:18][CH2:19][CH3:20])=[O:17])=[C:11]3[N:10]=[CH:9][CH:8]=2)[CH:2]=1.[CH2:21]([O:23]CCO)[CH3:22].[H-].[Na+].[H-]>>[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([C:7]2[N:12]3[N:13]=[CH:14][C:15]([C:16]([O:18][CH2:19][CH2:20][O:23][CH2:21][CH3:22])=[O:17])=[C:11]3[N:10]=[CH:9][CH:8]=2)[CH:2]=1

참가 물질

5

반응물 4

HCID 8076Glycol monoethyl etherHCID 24758Sodium hydrideHCID 166653HydrideHCID 11196438ETHYL 7-(PYRIDIN-3-YL)PYRAZOLO[1,5-A]PYRIMIDINE-3-CARBOXYLATE

생성물 1

HCID 21163083HCID 21163083, 화합물

실험 절차

To a mixture of ethyl 7-(3-pyridyl)pyrazolo[1,5-a]pyrimidine-3-carboxylate and 2-ethoxyethanol is added sodium hydride. After the hydride is reacted, the mixture is heated on a steam bath for 12 hours. The solvent is removed and the residue is acidified with dilute acetic acid to give the product of the example.

후처리

  1. temperaturethe mixture is heated on a steam bath for 12 hours
  2. customThe solvent is removed
  3. customto give the product of the example

출처 및 근거

ORD 기록
ord-990130447918491cb3a08531fd5ef381
출처 데이터셋
uspto-grants-1981_07
특허 번호
US04281000

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