Sulfuric acid magnesium salt (1:1) → Methyl (2E)-{[(2,4-dimethoxyphenyl)methyl]imino}acetate

HRID 127884

반응식

HRID 127884 반응식
[CH3:1][O:2][C:3]1[CH:10]=[C:9]([O:11][CH3:12])[CH:8]=[CH:7][C:4]=1[CH2:5][NH2:6].S([O-])([O-])(=O)=O.[Mg+2].[C:19]([O:23][CH3:24])(=[O:22])[CH:20]=O>C(Cl)Cl>[CH3:1][O:2][C:3]1[CH:10]=[C:9]([O:11][CH3:12])[CH:8]=[CH:7][C:4]=1[CH2:5][N:6]=[CH:20][C:19]([O:23][CH3:24])=[O:22]

참가 물질

5

반응물 3

HCID 24083Sulfuric acid magnesium salt (1:1)HCID 70205Acetic acid, 2-oxo-, methyl esterHCID 5972502,4-Dimethoxybenzylamine

생성물 1

HCID 23470137Methyl (2E)-{[(2,4-dimethoxyphenyl)methyl]imino}acetate

시약·촉매·용매 1

HCID 6344Dichloromethane용매2회

실험 절차

To a mixture containing 16.82 g (0.101 mole) of 2,4-dimethoxybenzylamine and anhydrous magnesium sulfate in 150 ml of methylene chloride at 25° is added a solution of 10.05 g (0.114 mole) of methyl glyoxalate in 20 ml of methylene chloride. The reaction mixture is stirred at room temperature overnight (15 hours) and then is filtered and the solvents are removed in vacuo to afford the imine as a dark orange gum.

후처리

  1. filtrationis filtered
  2. customthe solvents are removed in vacuo

출처 및 근거

ORD 기록
ord-3a6afd3455a641c0957d904292864f54
출처 데이터셋
uspto-grants-1981_03
특허 번호
US04257947

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