Piperidine → 4-[(1-Methyl-4-phenylindol-3-yl)methylene]-3-pyridino[3,4-e]pyridin-2-yl-2-pyrazolin-5-one

참여 물질

반응 조건

반응 단계

A mixture of the above pyrazolone, (VIk) (10 mg, 0.047 mmol), 5,6-methylenedioxy-1-methyl-indole-3-carboxaldehyde (11 mg, 0.054 mmol) in 1 mL of absolute ethanol along with a drop of piperidine was kept under stirring at 85-90° C. A solid separated. After 2 h the mixture was cooled to room temperature and the solid was filtered, washed with ethanol and dried to isolate the product (11 mg, 59% yield). MS: 398 (M+H).

출처 및 근거