Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Boc-D-Tyr(Bzl)-Oh → Boc-(D)-Tyr-Pro p-cyanobenzylamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Boc-D-Tyr(Bzl)-Oh | HCID 6992575 | — |
| 반응물 | Boc-(D)-Tyr(Bzl)-Pro p-cyanobenzylamide | HCID 131723502 | — |
| 용매 | Methanol | HCID 887 | — |
| 용매 | Palladium | HCID 23938 | — |
| 생성물 | Boc-(D)-Tyr-Pro p-cyanobenzylamide | HCID 131723501 | — |
반응 단계
12.5 g of Boc-(D)-Tyr(Bzl)OH were converted as in Example 3 into 18.9 g of Boc-(D)-Tyr(Bzl)-Pro-p-cyanobenzylamide, dissolved in 780 ml of MeOH and hydrogenated with Pd/C at room temperature. After 6 h, the catalyst was filtered off and the solvent was stripped off. Boc-(D)-Tyr-Pro-p-cyanobenzylamide was obtained in quantitative yield.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06455671B1 |
| 출처 데이터셋 | uspto-grants-2002_09 |
| ORD ID | ord-07ed3033b6b14ef797fc17a296793ec0 |
| 출처 메모 | uspto-grants-2002_09 |