Hydrochloric Acid → Aurone

반응식

C([C:4]1[CH:5]=[C:6]([CH:9]=[CH:10][CH:11]=1)[CH:7]=O)(O)=O.Cl.[O:13]1[CH2:18][CH2:17][O:16][CH2:15][CH2:14]1>>[CH:11]1[CH:4]=[CH:5][C:6](/[CH:7]=[C:17]2/[C:18]([C:14]3[C:15]([O:16]/2)=[CH:10][CH:11]=[CH:4][CH:5]=3)=[O:13])=[CH:9][CH:10]=1

참가 물질

반응물 3

HCID 313Hydrochloric Acid

HCID 120773-Carboxybenzaldehyde

HCID 312751,4-Dioxane

생성물 1

HCID 6537099Aurone

실험 절차

This product was immediately dissolved in dioxane (50 ml.), 3-carboxybenzaldehyde (4.5 g., 0.03 mole) added, followed by concentrated hydrochloric acid (10 ml) and the solution heated on a steam bath for 15 minutes. Work up was as Example 49 with recrystallisation from dimethylformamide to give the desired aurone, m.p. 280° C.