N-bromobutanimide → 2-Bromo-6-chlorobenzyl bromide

HRID 128244노트

반응식

HRID 128244 반응식
[Br:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([Cl:8])[C:3]=1[CH3:9].[Br:10]N1C(=O)CCC1=O>C(Cl)(Cl)(Cl)Cl>[Br:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([Cl:8])[C:3]=1[CH2:9][Br:10]

참가 물질

4

반응물 2

HCID 67184N-bromobutanimideHCID 1235522-Bromo-6-chlorotoluene

생성물 1

HCID 27568722-Bromo-6-chlorobenzyl bromide

시약·촉매·용매 1

HCID 5943Carbon Tetrachloride용매

실험 절차

2-bromo-6-chlorotoluene (20.55 g) and N-bromosuccinimide (19.6 g) were stirred together in carbon tetrachloride (100 ml) under reflux for 22 hours exposure to radiation from an infrared lamp. The resulting solution was cooled in ice, filtered and evaporated to yield the title product which was dissolved in petroleum ether (60-80). Part was recrystallised therefrom as pink needles (8.5 g) and part was recovered by evaporation as a dark orange solid (17.7 g) (total yield 26.2 g. 92%).

후처리

  1. temperatureunder reflux for 22 hours exposure to radiation from an infrared lamp
  2. temperatureThe resulting solution was cooled in ice
  3. filtrationfiltered
  4. customevaporated

출처 및 근거

ORD 기록
ord-1beeabfd933d4bed91e4baad702c8eeb
출처 데이터셋
uspto-grants-1981_03
특허 번호
US04259349

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