Hydrazine hydrate (1:1) → 2,3,5-Trichloro-6-hydrazinylpyrazine

HRID 1283729노트

반응식

HRID 1283729 반응식
[Cl:1][C:2]1[N:7]=[C:6]([Cl:8])[C:5]([Cl:9])=[N:4][C:3]=1Cl.O.[NH2:12][NH2:13]>O1CCOCC1.C(O)C>[Cl:1][C:2]1[C:3]([NH:12][NH2:13])=[N:4][C:5]([Cl:9])=[C:6]([Cl:8])[N:7]=1

참가 물질

5

반응물 2

HCID 24654Hydrazine hydrate (1:1)HCID 311820Tetrachloropyrazine

생성물 1

HCID 215166242,3,5-Trichloro-6-hydrazinylpyrazine

시약·촉매·용매 2

HCID 702Ethanol용매HCID 312751,4-Dioxane용매

반응 조건

온도
23 °C

실험 절차

A solution was prepared by dissolving 21.8 grams of tetrachloropyrazine in 100 milliliters of dioxane. The solution was diluted with 250 milliliters of ethanol and 15 milliliters of hydrazine hydrate was slowly added thereto. The temperature rose from 23°C to 37°C. The solution was held, with stirring, at 23°C for 20 minutes and the 3,5,6-trichloro-2-hydrazinopyrazine product was isolated by pouring the reaction mixture in water and filtering off the solid product. The product melted at 167°-168°C and was recovered in a yield of 20.2 grams (94 percent of theoretical).

후처리

  1. customA solution was prepared
  2. additionwas slowly added
  3. customrose from 23°C to 37°C

출처 및 근거

ORD 기록
ord-3b4444603e294af58d9ae11a28c2bb20
출처 데이터셋
uspto-grants-1976_08
특허 번호
US03976644

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