Ethyl formate → HCID 21515920, 화합물

반응식

[F:1][C:2]([C:13]1[CH:20]=[CH:19][CH:18]=[CH:17][C:14]=1[CH2:15][NH2:16])([F:12])[C:3]([F:11])([F:10])[C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1.[CH:21](OCC)=[O:22]>>[F:1][C:2]([C:13]1[CH:20]=[CH:19][CH:18]=[CH:17][C:14]=1[CH2:15][NH:16][CH:21]=[O:22])([F:12])[C:3]([F:11])([F:10])[C:4]1[CH:5]=[CH:6][CH:7]=[CH:8][CH:9]=1

참가 물질

반응물 2

HCID 8025Ethyl formate

HCID 203722482-(alpha,alpha,beta,beta-Tetrafluorophenethyl)benzylamine

생성물 1

HCID 21515920HCID 21515920, 화합물

실험 절차

2-(α,α,β,β-Tetrafluorophenethyl)benzylamine, 1.4 g. (0.005 mole), in 100 ml. of ethyl formate, is stirred and heated to refluxing for about 20 hours. Evaporation of the solution to dryness and trituration of the residual solid with petroleum ether gives N-[2-(α,α,β,β-tetrafluorophenethyl)benzyl]formamide, m.p. 61°-75°C.

후처리

temperatureheated
temperatureto refluxing for about 20 hours
customEvaporation of the solution to dryness and trituration of the residual solid with petroleum ether

출처 및 근거

ORD 기록: ord-45fe016111984fd9a917312ebb0d4386
출처 데이터셋: uspto-grants-1976_08
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US03978127

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