Boron trifluoride → HCID 13588518, 화합물

HRID 1284441노트

반응식

HRID 1284441 반응식
[C:1]([OH:16])(=[O:15])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][C:7]#[C:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH3:14].B(F)(F)F>C(O)(CC)C.CCOCC>[C:1]([O:16][CH:2]([CH2:3][CH3:4])[CH3:1])(=[O:15])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][C:7]#[C:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH3:14]

참가 물질

5

반응물 2

HCID 6356Boron trifluorideHCID 53127097-Tetradecynoic acid

생성물 1

HCID 13588518HCID 13588518, 화합물수율 170.5%

시약·촉매·용매 2

HCID 3283Diethyl Ether용매HCID 6568(+-)-2-Butanol용매

실험 절차

A solution of 7-tetradecynoic acid (1.22 g) and BF3 -etherate (1 ml) in 20 ml of sec-butyl alcohol was refluxed for 18 hours. The solution was diluted with ether and washed with saturated Na2CO3 solution, water, 2N NaOH, water, and saturated NH4Cl solution. The ether layer was dried (MgSO4) and the solvent removed under reduced pressure to give 1.30 g of sec-butyl 7-tetradecynoate as a yellow liquid.

후처리

  1. washwashed with saturated Na2CO3 solution, water, 2N NaOH, water, and saturated NH4Cl solution
  2. dry with materialThe ether layer was dried (MgSO4)
  3. customthe solvent removed under reduced pressure

출처 및 근거

ORD 기록
ord-0ae7ca54a92c4c50b37642c9ed474bc5
출처 데이터셋
uspto-grants-1986_01
특허 번호
US04563348

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