Phenyl Isothiocyanate → 5-(4-Benzyloxycarbonylaminobutyl)-3-phenyl-2-thiohydantoin

HRID 1287295

반응식

CO[C:3](=[O:21])[C@H:4]([CH2:6][CH2:7][CH2:8][CH2:9][NH:10][C:11]([O:13][CH2:14][C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1)=[O:12])[NH2:5].[C:22]1([N:28]=[C:29]=[S:30])[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1>>[CH2:14]([O:13][C:11]([NH:10][CH2:9][CH2:8][CH2:7][CH2:6][CH:4]1[NH:5][C:29](=[S:30])[N:28]([C:22]2[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=2)[C:3]1=[O:21])=[O:12])[C:15]1[CH:16]=[CH:17][CH:18]=[CH:19][CH:20]=1

참가 물질

반응물 2

HCID 7673Phenyl Isothiocyanate

HCID 6994982methyl (2S)-2-amino-6-(phenylmethoxycarbonylamino)hexanoate

생성물 1

HCID 215076815-(4-Benzyloxycarbonylaminobutyl)-3-phenyl-2-thiohydantoin

실험 절차

Using an analogous procedure to Example 1 Nε-benzyloxycarbonyl-L-lysine methyl ester may be reacted with phenyl isothiocynate to give the title compound.

출처 및 근거

ORD 기록: ord-b04fb705141b4f2b9c938a95305ca5cb
출처 데이터셋: uspto-grants-1976_10
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US03984430

연결된 노트

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