Hydrochloric Acid → HCID 86734074, 화합물
반응식
[CH3:1][C:2]1[N:3]=[CH:4][S:5][C:6]=1[CH3:7].C1(NC2CCCCC2)CCCCC1.[S:21]1[CH:25]=[CH:24][CH:23]=[C:22]1[C:26]([OH:28])=[O:27].O.Cl>C(OCC)(=O)C>[CH3:1][C:2]1[N:3]=[CH:4][S:5][C:6]=1[CH3:7].[S:21]1[CH:25]=[CH:24][CH:23]=[C:22]1[C:26]([OH:28])=[O:27]참가 물질
5
실험 절차
11.7 g. (0.033 mole) of 4,5-dimethylthiazole-2-thiolcarboxylic acid dicyclohexylamine salt, dissolved in 175 ml. of water and 175 ml. of ethyl acetate, was cooled and acidified with 6N hydrochloric acid to pH 2.2. The layers were separated and the aqueous phase was extracted with 2 × 75 ml. of ethyl acetate. The combined organic phases were dried over magnesium sulfate, filtered and evaporated under reduced pressure yielding 4.6 g. (80%) of a red solid. Infrared spectrum was consistent with the desired material.
후처리
- customThe layers were separated
- extractionthe aqueous phase was extracted with 2 × 75 ml
- dry with materialThe combined organic phases were dried over magnesium sulfate
- filtrationfiltered
- customevaporated under reduced pressure
- customyielding 4.6 g
출처 및 근거
- ORD 기록
- ord-364e8ec71fb9429c822e1aa4b9931f3e
- 출처 데이터셋
- uspto-grants-1976_10
- 특허 번호
- US03985740
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