Sodium Hydroxide → Thiourea, (2,3-dihydro-1H-inden-2-yl)-

HRID 1287896노트

반응식

HRID 1287896 반응식
C([NH:9][C:10]([NH:12][CH:13]1[CH2:21][C:20]2[C:15](=[CH:16][CH:17]=[CH:18][CH:19]=2)[CH2:14]1)=[S:11])(=O)C1C=CC=CC=1.[OH-].[Na+]>O>[CH2:14]1[C:15]2[C:20](=[CH:19][CH:18]=[CH:17][CH:16]=2)[CH2:21][CH:13]1[NH:12][C:10]([NH2:9])=[S:11]

참가 물질

4

반응물 2

HCID 14798Sodium HydroxideHCID 21507070N-[(2,3-Dihydro-1H-inden-2-yl)carbamothioyl]benzamide

생성물 1

HCID 5277341Thiourea, (2,3-dihydro-1H-inden-2-yl)-

시약·촉매·용매 1

HCID 962Water용매

실험 절차

1-Benzoyl-3-(2-indanyl)thiourea (0.931 g.) and sodium hydroxide (0.500 g.) were refluxed in water (6 ml.) for 10 minutes. The mixture was cooled, extracted into chloroform and the chloroform extracts washed with water, dried (MgSO4) and evaporated to give a white solid. Recrystallisation from ethanol/water afforded the title compound as platelets (0.647 g.), m.p. 155.0° C.

후처리

  1. temperatureThe mixture was cooled
  2. extractionextracted into chloroform
  3. washthe chloroform extracts washed with water
  4. dry with materialdried (MgSO4)
  5. customevaporated
  6. customto give a white solid
  7. customRecrystallisation from ethanol/water

출처 및 근거

ORD 기록
ord-9d356a509a3d42e49cfaea50e67a49e6
출처 데이터셋
uspto-grants-1976_10
특허 번호
US03985898

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