Ethanol → Ethyl 3-(5-methoxynaphthalen-2-yl)prop-2-enoate

HRID 1288210노트

반응식

HRID 1288210 반응식
[CH3:1][O:2][C:3]1[CH:12]=[CH:11][CH:10]=[C:9]2[C:4]=1[CH:5]=[CH:6][C:7]([CH:13]=[CH:14][C:15]([OH:17])=[O:16])=[CH:8]2.S(=O)(=O)(O)O.[CH2:23](O)[CH3:24]>C(Cl)(Cl)Cl>[CH3:1][O:2][C:3]1[CH:12]=[CH:11][CH:10]=[C:9]2[C:4]=1[CH:5]=[CH:6][C:7]([CH:13]=[CH:14][C:15]([O:17][CH2:23][CH3:24])=[O:16])=[CH:8]2

참가 물질

5

반응물 3

HCID 702EthanolHCID 1118Sulfuric AcidHCID 544606323-(5-Methoxynaphthalen-2-yl)prop-2-enoic acid

생성물 1

HCID 53889879Ethyl 3-(5-methoxynaphthalen-2-yl)prop-2-enoate

시약·촉매·용매 1

HCID 6212Chloroform용매

실험 절차

β-(5-methoxynaphth-2-yl)propenoic acid (0.075 moles) is allowed to reflux with 8-10 pieces of Orierite in absolute ethanol (20 ml) containing concentrated sulfuric acid (5 ml) for 21 hours. The cooled reaction mixture is diluted with chloroform and filtered hot. The filtrate is washed 3 times with water, once with 10% sodium bicarbonate and twice more with water. After drying over sodium sulfate, the solvent is removed to give ethyl β-(5-methoxynaphth-2-yl)propenoate.

후처리

  1. customThe cooled reaction mixture
  2. filtrationfiltered hot
  3. washThe filtrate is washed 3 times with water
  4. dry with materialAfter drying over sodium sulfate
  5. customthe solvent is removed

출처 및 근거

ORD 기록
ord-8496e4432d85419ca57085f72da427d3
출처 데이터셋
uspto-grants-1976_10
특허 번호
US03987116

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