Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ammonia → N-(2-phenoxypropyl)phenylacetamidine p-toluenesulphonate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ammonia | HCID 222 | — |
| 반응물 | 2-Phenoxy-1-propanamine | HCID 3718355 | — |
| 반응물 | Phenylacetamidine p-toluenesulphonate | HCID 21504266 | — |
| 용매 | Ethanol | HCID 702 | — |
| 용매 | Diethyl Ether | HCID 3283 | — |
| 생성물 | N-(2-phenoxypropyl)phenylacetamidine p-toluenesulphonate | HCID 178457535 | — |
반응 단계
2-Phenoxypropylamine (6.0 g.) was added to a suspension of phenylacetamidine p-toluenesulphonate (12.4 g.) in absolute ethanol (20 ml.). The mixture was heated to reflux for 4 hours by which time the initially vigorous evolution of ammonia had practically ceased. The resulting solution was cooled somewhat and diluted with ether to give an oil which rapidly crystallised on scratching. The solid was filtered and recrystallised from a mixture of ethanol and water to give N-(2-phenoxypropyl)phenylacetamidine p-toluenesulphonate, m.p. 127°-129°.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US03987158 |
| 출처 데이터셋 | uspto-grants-1976_10 |
| ORD ID | ord-719982c498de4dda8dc06af693ee3417 |
| 출처 메모 | uspto-grants-1976_10 |