Ethanol → HCID 85437759, 화합물

HRID 1288232노트

반응식

HRID 1288232 반응식
[CH3:1][C:2]1[CH:3]=[C:4]([CH:10]=[CH:11][CH:12]=1)[O:5][CH2:6][C:7](=O)[CH3:8].C(O)C.Cl.[NH2:17][OH:18]>O>[CH3:1][C:2]1[CH:3]=[C:4]([CH:10]=[CH:11][CH:12]=1)[O:5][CH2:6][C:7](=[N:17][OH:18])[CH3:8]

참가 물질

5

반응물 3

HCID 702EthanolHCID 3095751-(3-Methylphenoxy)-2-propanoneHCID 443297Hydroxyamine hydrochloride

생성물 1

HCID 85437759HCID 85437759, 화합물

시약·촉매·용매 1

HCID 962Water용매

실험 절차

1-(3-Methylphenoxy)propan-2-one (24.9 g.) and ethanol (100 ml.) were added to a solution of hydroxylamine hydrochloride (25 g.) and fused sodium acetate (25 g.) in water (110 ml.). The resulting solution was refluxed for 31/2 hours and evaporated to near dryness under reduced pressure. The residue was partitioned between water and ether. The ether extract was washed with water, dried over anhydrous potassium carbonate and evaporated. The residue was distilled to give a fraction, b.p. 159°-163°/12 mm. Redistillation gave 1-(3-methylphenoxy)propan-2-one oxime, b.p. 165°-167°/13 mm.

후처리

  1. temperatureThe resulting solution was refluxed for 31/2 hours
  2. customevaporated
  3. customThe residue was partitioned between water and ether
  4. extractionThe ether extract
  5. washwas washed with water
  6. dry with materialdried over anhydrous potassium carbonate
  7. customevaporated
  8. distillationThe residue was distilled
  9. customto give a fraction, b.p. 159°-163°/12 mm
  10. distillationRedistillation

출처 및 근거

ORD 기록
ord-d963b52bf86449b7b7505952619039e9
출처 데이터셋
uspto-grants-1976_10
특허 번호
US03987158

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