Acetic Anhydride → 4-Acetylamino-3,5-bis-trifluoromethylnitrobenzene
반응식
[N+:1]([C:4]1[CH:10]=[C:9]([C:11]([F:14])([F:13])[F:12])[C:7]([NH2:8])=[C:6]([C:15]([F:18])([F:17])[F:16])[CH:5]=1)([O-:3])=[O:2].[C:19](OC(=O)C)(=[O:21])[CH3:20]>N1C=CC=CC=1>[C:19]([NH:8][C:7]1[C:6]([C:15]([F:16])([F:17])[F:18])=[CH:5][C:4]([N+:1]([O-:3])=[O:2])=[CH:10][C:9]=1[C:11]([F:12])([F:13])[F:14])(=[O:21])[CH3:20]참가 물질
4
실험 절차
A mixture of 8.2 g. of 4-nitro-2,6-bis-trifluoromethylaniline, 3.6 g. acetic anhydride, and 20 ml. of pyridine is heated for 48 hours on a steam bath. The reaction mixture is poured onto ice water and the solid material is filtered, dried and recrystallized from isopropanol affording 4-acetylamino-3,5-bis-trifluoromethylnitrobenzene.
후처리
- additionA mixture of 8.2 g
- additionThe reaction mixture is poured onto ice water
- filtrationthe solid material is filtered
- customdried
- customrecrystallized from isopropanol
출처 및 근거
- ORD 기록
- ord-3e64137d90cc4df998af2122dc599261
- 출처 데이터셋
- uspto-grants-1976_10
- 특허 번호
- US03987199
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