Trimethylsilyl iodide → 207669-62-3

HRID 1289349

반응식

HRID 1289349 반응식
C[O:2][CH:3]1[CH2:8][CH2:7][CH:6]([CH2:9][Br:10])[CH2:5][CH2:4]1.C[Si](I)(C)C>C(Cl)(Cl)Cl>[Br:10][CH2:9][CH:6]1[CH2:7][CH2:8][CH:3]([OH:2])[CH2:4][CH2:5]1

참가 물질

4

반응물 2

HCID 85247Trimethylsilyl iodideHCID 217065291-(Bromomethyl)-4-methoxycyclohexane

생성물 1

HCID 21832707207669-62-3

시약·촉매·용매 1

HCID 6212Chloroform용매

실험 절차

The 4-methoxycyclohexylbromomethane compound (C-4) (2.6 g) in chloroform (7.8 g) was cooled with ice. Then trimethylsilyliodide (2.2 ml) was transferred to the C-4 solution. It was stirred at ambient temperature for 8 h, and then quenched with methanol. Then, volatiles were removed to obtain the desired alcohol in almost quantitative yield.

후처리

  1. customquenched with methanol
  2. customThen, volatiles were removed

출처 및 근거

ORD 기록
ord-7df562be99754e0aaf4e0a7c5c27f733
출처 데이터셋
uspto-grants-1998_05
특허 번호
US05750300

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