1,2-Dichloroethane → Methyl 3-(4-chlorophenyl)-2-propenoate

HRID 1289786

반응식

HRID 1289786 반응식
[Cl:1][C:2]1[CH:12]=[CH:11][C:5]([CH:6]=[CH:7][C:8]([OH:10])=[O:9])=[CH:4][CH:3]=1.Cl[CH2:14]CCl.S(=O)(=O)(O)O>CO>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([CH:6]=[CH:7][C:8]([O:10][CH3:14])=[O:9])=[CH:11][CH:12]=1

참가 물질

5

반응물 3

HCID 111,2-DichloroethaneHCID 1118Sulfuric AcidHCID 153712-Propenoic acid, 3-(4-chlorophenyl)-

생성물 1

HCID 98955Methyl 3-(4-chlorophenyl)-2-propenoate수율 95%

시약·촉매·용매 1

HCID 887Methanol용매

실험 절차

The synthesis method of Example 7-(1) was applied. 4-Chlorocinnamic acid (10.0 g), 1,2-dichloroethane (50 methanol (9.0 ml) and concentrated sulfuric acid (0.4 ml) were used as reagents to give 10.2 g of a white solid (yield 95%).

출처 및 근거

ORD 기록
ord-0677265866c244d1aee9377bcdf37155
출처 데이터셋
uspto-grants-1998_05
특허 번호
US05750545

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