Methane → Octahydro-6,6-diphosphono-1-(2-mercaptoethyl)-1-methyl-1-pyrindinium chloride

HRID 1290655노트

반응식

HRID 1290655 반응식
[Br-].[P:2]([C:6]1([P:22]([OH:25])([OH:24])=[O:23])[CH2:14][CH:13]2[CH:8]([CH2:9][CH2:10][CH2:11][N+:12]2([CH2:16][CH2:17][S:18]C(=O)C)[CH3:15])[CH2:7]1)([OH:5])([OH:4])=[O:3].C.[ClH:27]>>[Cl-:27].[P:22]([C:6]1([P:2]([OH:5])([OH:4])=[O:3])[CH2:14][CH:13]2[CH:8]([CH2:9][CH2:10][CH2:11][N+:12]2([CH2:16][CH2:17][SH:18])[CH3:15])[CH2:7]1)([OH:24])([OH:25])=[O:23]

참가 물질

4

반응물 3

HCID 297MethaneHCID 313Hydrochloric AcidHCID 18916577HCID 18916577, 화합물

생성물 1

HCID 86752569Octahydro-6,6-diphosphono-1-(2-mercaptoethyl)-1-methyl-1-pyrindinium chloride

실험 절차

Octahydro-6,6-diphosphono-1-(2-acetylthioethyl)-1-methyl-1-pyrindinium bromide (0.05 mmol) is heated at reflux in 6N HCl (15 ml) under an atmosphere of nitrogen. The reaction mixture is cooled, treated with charcoal and filtered. The resulting filtrate is concentrated under reduced pressure. The resulting solid residue can be recrystallized from water and ethanol to provide the desired product.

후처리

  1. temperatureThe reaction mixture is cooled
  2. filtrationfiltered
  3. concentrationThe resulting filtrate is concentrated under reduced pressure
  4. customThe resulting solid residue can be recrystallized from water and ethanol

출처 및 근거

ORD 기록
ord-a7c1acfee915465a822acf10115a7627
출처 데이터셋
uspto-grants-1998_05
특허 번호
US05753634

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